Love Wallpaper Biography
Basic research is the study of the fundamental molecular mechanisms that drive life. It covers every aspect of cellular function, from the way cells process nutrients, grow, and divide, to the way they die. Basic researchers use human cells and animal models to ask questions like: How do cells communicate with one another and their environments? How do they respond to stress? What role do chemical changes to protein structure play in these processes?
The answers to these questions help scientists establish a baseline for what's normal. Then, they can begin asking questions about what happens when genetic or environmental changes perturb a cell and alter its behavior.
It's difficult to know where breakthroughs will come from. Progress in one research area provides data for other areas. So basic scientists share their findings with other scientists by publishing papers in scientific journals. Their peers—and future generations—build upon these findings.
At Sanford-Burnham, Dr. Gregg Duester is proud to be a basic researcher. Researchers in his lab study retinoic acid, an active form of vitamin A. They want to know how retinoic acid tells the right body parts to form in the right places at the right time in a developing embryo. To figure out retinoic acid's role, they compare mice with and without the ability to convert vitamin A to retinoic acid. In a paper published in the scientific journal PLoS Biology, Dr. Duester and his team made an important discoveryabout the part of the developing brain that makes retinoic acid and its impact on the production of inhibitory neurons—the type of neuron that keeps functions like memory and learning in check.
Love Wallpaper
Love Wallpaper
Love Wallpaper
Love Wallpaper
Love Wallpaper
Love Wallpaper
Love Wallpaper
Love Wallpaper
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